Anabolic
Definition
Anabolic refers to metabolic processes that build complex molecules from simpler ones, requiring energy input. In the context of peptide research, anabolic processes include muscle protein synthesis, collagen production, and bone formation. Growth hormone secretagogues, IGF-1 LR3, and follistatin promote anabolic pathways through different mechanisms — GH/IGF-1 axis stimulation and myostatin inhibition respectively.
Related Terms
Related Compounds
IGF1-LR3
An in-depth review of IGF1-LR3, a long-acting insulin-like growth factor-1 variant with enhanced bioavailability, covering its mechanism of action, pharmacokinetics, research applications in muscle growth, cell proliferation, anabolic pathways, and safety profile.
Read monographFollistatin
An in-depth review of Follistatin (FST-344), covering its isoforms, mechanism of myostatin and activin neutralization, gene therapy applications for muscular dystrophies, metabolic effects, and clinical trial data.
Read monographSermorelin
An in-depth review of Sermorelin (GHRH 1-29), a growth hormone-releasing hormone analog, covering its mechanism of action, pharmacokinetics, safety profile, research applications in GH stimulation, anti-aging, and pituitary function preservation.
Read monographRelated Studies
Follistatin gene delivery enhances muscle growth and strength in nonhuman primates
Kota J, Handy CR, Haidet AM, et al. · Science Translational Medicine (2009)
Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin
Gilson H, Schakman O, Kalista S, et al. · American Journal of Physiology-Endocrinology and Metabolism (2009)
Regulation of myostatin activity and muscle growth
Lee SJ, McPherron AC · Proceedings of the National Academy of Sciences (2001)
Growth hormone-releasing hormone and aging
Merriam GR, Schwartz RS, Vitiello MV · Endocrine (2001)