Biochemistry
Peptide Bond
Definition
A peptide bond is a covalent chemical bond formed between the carboxyl group of one amino acid and the amino group of another, with the loss of a water molecule (condensation reaction). This amide bond is the fundamental linkage that connects amino acids in a peptide chain. Peptide bonds are planar and relatively rigid, which influences the overall three-dimensional folding of the peptide. The number of peptide bonds in a chain is one fewer than the number of amino acids.