research-methods
In Vivo
Definition
In vivo (Latin for 'within the living') refers to experiments conducted within a whole living organism, such as animal models or clinical human trials. In vivo studies assess systemic pharmacokinetics, tissue distribution, efficacy, toxicity, and behavioral outcomes that cannot be captured in cell-based assays. Most peptide research progresses from in vitro characterization to in vivo preclinical studies before any potential clinical translation.